A friend of mine bought me a sample of Joints + Bones for a shoulder injury I had. FORTUNATELY I did not use it at that time. Which was about a week prior to my total knee replacement surgery. Three days after my surgery the severe swelling and tightness of my skin around my knee was killing me. So looking in my medicine chest for something that may help is when I remembered.... the sample bottle of Joints + Bones. I figured cant hurt to try.... OMG what a pleasure and QUICK relief of the pain I was having! I immediately called my wife and asked her to go buy me a full size (not sample) bottle. Thank God for this product being available locally for me. I cannot thank you enough for the relief I get using this product. Not sure if this use is exactly what its intended for....BUT IT WORKS!!!! Again THANK YOU!!